Intraocular inflammation is a potentially sight-threatening disease causing a diagnostic challenge for ophthalmologists. Recently, there have been several advances in the investigations and treatment of uveitis. A tailored approach to the laboratory diagnosis of uveitic cases should be directed by the history, patient's symptoms and signs, and clinical examination. The treatment of uveitis is evolving with newer drugs and innovative advances in ocular drug delivery. This IC aims at providing at the management of newer investigations and treatment modalities of uveitis.